Married to model Cindy Crawford on May 29, 1998, they have two children, Presley, born July 2, 1999, and Kaia, born September 3, 2001. Gerber grew up in the Five Towns and graduated in 1980 from Hewlett High School in Long Island. He attended the University of Arizona and graduated with a BA in marketing. He currently lives in Los Angeles with his wife and children.

In May 2007, Delta Airlines began serving cocktails designed by Gerber.

His Midnight Bar Collection of drink mixes is now available to the public.